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KMID : 0607520100180010003
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Korean Journal of Psychosomatic Medicine
2010 Volume.18 No. 1 p.3 ~ p.10
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Transcranial Magnetic Stimulation in Gilles de la Tourette Syndrome
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Lee Moon-Soo
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Abstract
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Gilles de la Tourette syndrome is a chronic motor and vocal tic disorder of childhood onset. Abnornmalities in basal ganglia-thalamo-cortical circuits may play an important role in the pathophysiology underlying the involuntary tics. It is often complicated by comorbid attention-deficit/hyperactivity disorder or obsessive-compulsive disorder. Transcranial magnetic stimulation(TMS) is a neurophysiologic technique with research ap-plication. As there is good evidence that this technique can modify cortical activity, repetitive TMS is also used for treatment to change the cortical excitability and therefore affect underlying interconnected cortical-sub-cortical loop. We reviewed the neurophysiologic parameters and the clinical applicability of TMS and rTMS.
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KEYWORD
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Transcranical magnetic stimulation, Tourette syndrome, Motor evoked potential
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